Faculty & Staff
Robert Frisina
Education
- Post-Doctoral, Center for Brain Research University Rochester, Rochester, New York (1985)
- Ph.D. in Bioengineering, Physiology, Neuroscience, Syracuse University, New York (1983)
- Bachelors in Experimental Psychology and Economics, Hamilton College, New York (1977)
Research Areas
Development of Bio-therapeutic Systems, Devices and Compounds for Treating Sensory Deficits; Emphasis on Bench-to-Bedside Investigations of the Auditory System, and Translational Research on Deafness and Other Neuroengineering Applications.
MEMBERSHIPS
2019 - Fellow, American Association for the Advancement of Science - AAAS
2019 - Senior Member, National Academy of Inventors - NAI
2018 - Senior Member – IEEE
2017 - Fellow, Biomedical Engineering Society - BMES
2016 - Fellow, American Institute for Medical and Biological Engineering – AIMBE
2013 - American Association for the Advancement of Science - AAAS
2013 - Biomedical Engineering Society – BMES
2012 - Member, IEEE
2011- National Academy of Inventors - NAI
1991-2009 - American Speech, Language, Hearing Association - ASHA
1990-2009 - Scientific Fellow, American Academy Otolaryngology-Head & Neck Surgery
1985-2010 - Charter Member, Society for Neuroscience, Rochester Chapter
1982 - Association for Research in Otolaryngology - ARO
1979 - Society for Neuroscience - SFN
1979 - International Brain Research Organization - IBRO
1979 - Fellow, Acoustical Society of America - ASA
1977 - Phi Beta Kappa
1977 - Sigma Xi; Psi Chi
COURSES TAUGHT
Guest Lecturer for Professional Seminar Series, Industrial & Management Systems Engineering Dept.- College of Engineering, Univ. of South Florida (1/19 to present)
Guest Lecturer for EML 4930/6930, Biomedical Devices & Materials, Mechanical Engineering Dept.- College of Engineering, Univ. of South Florida (8/16 to present)
Research Lecturer for Otolaryngology Department Surgical Resident Academic Seminar Series- University of South Florida Medical School (8/15 to present)
Course Director/Instructor for BME 4100/5105, Medical Engineering, Dept., Chemical & Biomedical Engineering- College of Engineering, Univ. of South Florida (1/11 to present)
Research Grants
NIH-National Cancer Institute (NCI) R01: “Genetic Susceptibility and Biomarkers of Platinum-Related Toxicities”
National Institutes of Health (NIDCD) R21; “Novel Biomedical Imaging Systems for Diagnosing Hearing Loss”
National Institutes of Health (NIDCD) R21; “Sex Effects for Hearing Loss Drug Therapies”
Honors and Awards
Fellow – IEEE, 2022-present
Outstanding Faculty Mentor Award, University of South Florida, 2020
Fellow – American Association for the Advancement of Science (AAAS), 2019-present.
Senior Member - National Academy of Inventors, University of South Florida, 2019-present.
IEEE Senior Member – 2018-present.
Fellow and Steering Committee Member - Florida Association for Nanobiotechnology
Distinguished University Professor – Univ. South Florida- Tampa, 2017-present; given
each year to 3 of ~2000 faculty members.
Fellow – Biomedical Engineering Society (BMES), 2017-present.
Fellow – American Institute for Medical & Biological Engineering (AIMBE), 2015-present.
Sr. Researcher of the Year Award, College of Engineering, University of South Florida,
2014
National Academy of Inventors, University of South Florida, 2011- present.
Fellow - Acoustical Society of America (ASA), 1994-present.
Scientific Fellow - American Academy of Otolaryngology - Head & Neck Surgery, 1990-2009.
Intellectual Property Productivity Award, Tech. Licensing Office, Rochester Inst.
Tech., 2007.
Distinguished Researcher in Biological Sciences, RIT, 2003-2007.
Silver Certificate, Acoustical Society of America, 2004.
Appointed to Technical Committee on Psychological & Physiological Acoustics by Executive
Council of the Acoustical Society of Am., 1988-2004; Chair -Subcomm. for National
Meetings, 1990-3.
National Institutes of Health FIRST Award in Communicative and Neurosensory Disorders,
1988-1994.
National Institutes of Health Fellow in Sensory Physiology and Biophysics, 1983-1986.
National Science Foundation Graduate Fellow in Physiology, 1978-1981.
Honorary Syracuse University Graduate Fellow, 1978-1981.
Syracuse University Graduate Fellowship, 1978-1979.
Root Fellow, 1977-1978, graduate award given by Hamilton College to 3 seniors who
have "shown marked ability & special aptitude for research in the depts. of science".
(Hamilton Catalog)
Syracuse University Graduate Scholar, 1977-1978.
Phi Beta Kappa, Sigma Xi, Psi Chi, 1977.
Summa Cum Laude A.B. Degree, 1977.
Departmental honors in Psychology and Economics, 1977.
Marder Prize, 1977, awarded to the senior who most excels in Psychology.
Certificate of Appreciation, Utica Volunteer Agency, 1977.
Bennet Scholar, 1976-77, honor bestowed upon the senior who completed their junior
year with distinction.
In 1976, a faculty committee chaired by the Dean of Hamilton College nominated one
senior for the Rhodes Scholarship and two seniors for the Marshall Scholarship.
Dean's List-High Honor, 1974-1977.
Gilbert Prize, 1974, presented for greatest scholastic improvement in the freshman
year.
New York State Regents Scholar, 1973-1977.
Bronze Citizenship Medal, Sons of the American Revolution, 1973.
Recent Publications
Note: *Asterisks indicate publications where Dr. Frisina’s trainee is an author (name italicized).
*Dinh, P.C., Monahan, P.O., Fossa, S.D., Sesso, H.D., Feldman, D.R., M. Dolan, M.E., Nevel, K., Kincaid, J., Vaughn, D.J., Martin, N.E., Sanchez, V., Einhorn, L.H., Frisina, R.D., Fung, C., Kroenke, K., Travis, L.B. (2024- In press) Impact of Pain and Adverse Health Outcomes on Long-term U.S. Testicular Cancer Survivors. J National Cancer Institute [Impact Factor ~10]
*Sanchez VA, Shuey MM, Dinh PC Jr, Monahan PO, Fosså SD, Sesso HD, Dolan ME, Einhorn LH, Vaughn DJ, Martin NE, Feldman DR, Kroenke K, Fung C, Frisina RD, Travis LB. (2023) Patient- Reported Functional Impairment Due to Hearing Loss and Tinnitus After Cisplatin-Based Chemotherapy. J Clin Oncol. JCO2201456. doi: 10.1200/JCO.22.01456. Epub ahead of print PMID: 36626694. [Impact Factor ~51]
*Penn, C., Mayilsamy, K., Zhu, X., Bauer, M.A., Mohapatra, S.S., Frisina, R.D., Mohapatra, S. (2023) A Mouse Model of Repeated Traumatic Brain Injury-induced Hearing Impairment: Early Cochlear Neurodegeneration in the Absence of Hair Cell Loss. Hearing Research. https://doi.org/10.1016/j.heares.2023.108832 [Impact Factor ~4]
Patil, M.J., Kim, S-H., Bahia, P.K., Nair, S.S., Darcey, T.S., Fiallo, J., Zhu, X., Frisina, R.D., Hadley, S.H., Taylor-Clark, T.E. (2023) A novel Flp reporter mouse shows that TRPA1 expression is largely limited to sensory neuron subsets. eNeuro., 10 (12) ENEURO.0350-23.2023; DOI: 10.1523/ENEURO.0350-23.2023 [Impact Factor ~5]
*Shahbazi, M., Zhang, X., , …, Sanchez, V…, Einhorn, L.H., Cox, N., Frisina, R.D., Travis, L.B., Dolan, M.E. (2023) Comprehensive Association Analysis of Speech Recognition Thresholds after Cisplatin-based Chemotherapy in Survivors of Adult-onset Cancer. Cancer Medicine, 12(3):2999-3012. doi: 10.1002/cam4.5218. [Impact Factor ~5]
Reavis, K.M., Bisgaard, N., Canlon, B., Dubno, J.R., Frisina, R.D., Hertzano, R., Humes, L.E., … Pichora-Fuller, M.K., Shuster, B., Singh, G. (2023) Sex-linked biology and gender-related research is essential to advancing hearing health. Ear & Hearing. 44(1):10-27. doi: 10.1097/AUD.0000000000001291. [Impact Factor ~4]
*Sanchez, VA, Dinh Jr., PC, Rooker, J, Monahan, PO, Althouse, SK, Fung, C, Sesso, HD, Einhorn, LH, Dolan, ME, Frisina, RD, Travis, LB. (2023) Prevalence and risk factors for ototoxicity after cisplatin-based chemotherapy. J Cancer Survivorship. https://doi.org/10.1007/s11764-022-01313-w [Impact Factor ~5]
*Zhang, X., , Trendowski, M.R., …, Sanchez, V., Frisina, R.D., Einhorn, L.H., Cox, N., Travis, L.B., Dolan, M.E. (2022) Pharmacogenomics of Cisplatin-Induced Neurotoxicities: Hearing Loss, Tinnitus and Peripheral Sensory Neuropathy. Cancer Medicine, 11 2801-2816. https://doi.org/10.1002/cam4.4644 [Impact Factor ~4]
*Febles, NK, Bauer, MA, Ding, B, Zhu, X, Gallant, ND, Frisina, RD. (2022) A combinatorial approach to protect sensory tissue against cisplatin-induced ototoxicity. Hearing Research. 415 https://doi.org/10.1016/j.heares.2022.108430 [Impact Factor ~4]
Ardeshirrouhanifard, S., Fossa, S.D., Huddart, R., Monahan, P., Fung, C., Dolan, E., Feldman, D.R., Hamilton, R.J., Vaughn, D., Martin, D., Kollmannsberger, C., Dinh, P., Einhorn, L., Frisina, R.D., Travis, L.B. (2022). Ototoxicity After Cisplatin-based Chemotherapy: Factors Associated with Discrepancies Between Patient-reported Outcomes and Audiometric Assessments. Ear & Hearing. 43(3):794-807. DOI: 10.1097/aud.0000000000001172 PMID: 35067571 PMCID: PMC9010341 [Impact Factor ~4]
*Forouzandeh, F., Ahamed, N.N., Zhu, X., Bazard, P., Goyal, K., Walton, J.P., Frisina, R.D., Borkholder, D.A. (2021) A wirelessly controlled scalable 3D-printed microsystem for drug delivery. Pharmaceuticals. 14(6), 538; https://doi.org/10.3390/ph14060538 [Impact Factor~5]
*Damnjanovic, R., Bazard, P., Frisina, R.D., Bhethanabotla, V.R. (2020) Hybrid Electro-Plasmonic Neural Stimulation with Visible Light Sensitive Gold Nanoparticles. ACS Nano. doi:10.1021/acsnano.0c00722. [Impact Factor ~15]
Kearns, S.L., Fung, C… R.D. Frisina…L.H. Einhorn, L.B. Travis (2020) Relationship of Cisplatin Related Adverse Health Outcomes with Disability and Unemployment Among Testicular Cancer Survivors. J. Nat. Cancer Inst. – Cancer Spectrum. doi: 10.1093/jncics/pkaa022 [Impact Factor ~14]
*Bazard, P., Ding, B., Chittam, H.K., Zhu, X., Parks, T.A., Taylor Clark, T.E., Bhethanabotla, V.R., Frisina, R.D., Walton, J.P. (2020) Aldosterone Upregulates Voltage Gated Potassium Currents and NKCC1 Protein Membrane Fractions. Nature Scientific Reports. 10, 15604. https://doi.org/10.1038/s41598-020-72450-4 [Impact Factor ~5]
Forouzandeh, F., Ahamed, N.N., Hsu, M-C., Walton, J.P., Frisina, R.D., Borkholder, D.A. (2020) A 3D-printed modular microreservoir for drug delivery. Micromachines. 11:648-665. Cover Article; doi: 10.3390/mi11070648 [Impact Factor~3]
*Mohapatra, S.S., Frisina, R.D., Damnjanovic, R., … Li, C., Santra, S., Phan, M-H. (2020) Advances in Translational Nanotechnology: Challenges and Opportunities. Applied Sciences.10(14), 4881; https://doi.org/10.3390/app10144881.
RECENT BOOKS, REVIEWS, CHAPTERS, & SHORT REPORTS:
Frisina, R.D, T.T. Williamson, X. Zhu and B. Ding (In Press, 2020) The Aging Cochlea. In: Fritzsch, B., Grothe, B. Eds.; The Senses - Vol. II Audition: A Comprehensive Reference, 2nd Edition. Elsevier, Amsterdam.
Frisina, R.D, C.J. Cruz, T.T. Williamson, X. Zhu and B. Ding (In Press, 2020) Emerging Clinical Translational Treatment Strategies for Age-Related Hearing Loss. In: Helfer, K., Bartlett, E.., Popper, A. & Fay, R.R. Eds.; The Aging Auditory System,. Springer Science+Business Media, LLC, New York.
Williamson, T.T. , X. Zhu, J. Pineros, B. Ding, R.D. Frisina (In Press, 2020) Understanding Hormones and Hormone Therapies’ Impacts on the Auditory System. J. Neurosci. Res.
Alex, C.S., Grinshpan, A., Bazard, P., Frisina, R.D. (In Press, 2020) A Mathematical Modeling of Infrared Neural Stimulation. Undergrad J Math Model.
PATENTS
United States
Forouzandeh, F., Borkholder, D.A, Frisina, R.D., Walton, J.P., Zhu, X. (2020-Pending) “Miniature Pumps”. Provisional Serial No.: 62/923,417.
Forouzandeh, F., Borkholder, D.A, Frisina, R.D., Walton, J.P., Zhu, X. (2020-Pending) “Implantable Drug Storage Devices for Drug Delivery”.
Borkholder, D.A, Forouzandeh, F., Ouyang, J., Smith, K., Carter, R., Mahajan, C., Cormier, D., Walton, J.P., Frisina, R.D. (2020-Pending) “Methods of Micropump Fabrication and Devices Thereof.”
Febles, N., Gallant, N., Ding, B., Frisina, R.D. (2020- Pending) “Otoprotective Formulations and Uses Thereof”. Provisional Serial No.: 15/894,213 .
Bazard, P., Frisina, R.D., Walton, J.P., Bhethanabotla, V.R. “Plasmonic stimulation of electrically excitable biological cells.” United States Patent No. 10,463,878B2 (Nov. 5, 2019).
Sunol, A.K., Jacobson, T., Rogers, E., Guardiano, S., Ticknor, E., Cogswell, K., Frisina, R.D., Passaglia, C. United States Patent No. 10,414,475- “Gas-Inflatable Personal Flotation Devices.” (Sept. 17, 2019).
Frisina, R.D., Walton, J.P., Ding, B., Zhu, X. “Hormone Treatment for Age-Related Hearing Loss- Presbycusis.” United States Patent No. 10,342,806 (July 9, 2019).
Bazard, P., Frisina, R.D., Walton, J.P., Bhethanabotla, V.R. “Plasmonic stimulation of electrically excitable biological cells.” United States Patent No. 9,937,359B1 (April 10, 2018).
Miller, K., Fuller, L., Taylor, J., Frisina, R.D. & Walton, J.P. “Hearing Aid with a Permanently-Adjusted Frequency Response”, United States Patent#: 5,406,633 (April, 1995).
Walton, J.P., Miller, K., Taylor, J., Fuller, L. & Frisina, R.D. “Aid to Hearing Speech in a Noisy Environment”, United States Patent#: 5,285,502 (February 1994).
International Patents
Walton, J.P., Miller, K., Taylor, J., Fuller, L., & Frisina, R.D. “Aid to Hearing
Speech in a Noisy Environment”, Serial#: PCT/US 93908361.4 (1996).